Prenatal PAH exposure is associated with chromosome-specific aberrations in cordblood

Chromosomal aberrations area ssociated with increased cancer risk in adults. Previously, we demonstrated that stable aberrations involving chromosomes 1–6 in cord blood are associated with prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) measured in air and are disproportionate to genomic content. We now examine whether the association with air PAHs is chromosome-specific and extends to smaller chromosomes.

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