Prenatal Bisphenol A Exposure and Child Behavior in an Inner City Cohort

Analysis was conducted on 198 children (87 boys and 111 girls). Among boys, high prenatal BPA exposure (highest quartile versus the lowest three quartiles) was associated with significantly higher CBCL scores (more problems) on Emotionally Reactive (1.62 times greater, 95% CI 1.13-2.32) and Aggressive Behavior syndromes (1.29 times greater, 95% CI 1.09, 1.53). Among girls, higher exposure was associated with lower scores on all syndromes, reaching statistical significance for Anxious/Depressed (0.75 times as high, 95% CI 0.57, 0.99) and Aggressive Behavior (0.82 times as high, 95% CI 0.70, 0.97). Conclusion: These results suggest that prenatal exposure to BPA may affect child behavior, and differently among boys and girls.

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